Skip to content
MarketScale
‹ Back to IndustriesHealthcare

How Mark Cuban is Turning the Prescription Drug Industry Upside Down

When Mark Cuban enters an industry, he typically disrupts it in one way or another. And that’s precisely what it appears he has done once again, though this time in the healthcare space. His Cost Plus Drug Company has turned the industry on its head and introduced transparency to the previously opaque area of prescription…

This story was produced through MarketScale. See how Healthcare teams put it to work with Executive Thought Leadership.

Share
How Mark Cuban is Turning the Prescription Drug Industry Upside Down

Get featured

Want to get featured in MarketScale Healthcare?

Create a free MarketScale workspace and get your company's expertise featured across our Healthcare coverage. No credit card, no demo required.

Start free

When Mark Cuban enters an industry, he typically disrupts it in one way or another. And that’s precisely what it appears he has done once again, though this time in the healthcare space. His Cost Plus Drug Company has turned the industry on its head and introduced transparency to the previously opaque area of prescription drug prices.

“We started [Mark Cuban Cost Plus Drug Company] with the goal of being the low-cost provider for generic drugs,” Cuban told MarketScale. 

The company’s website features a chart displaying the stark difference in the retail price of these drugs versus what consumers pay through their platform. But perhaps the most striking thing about the Cost Plus Drug Company is the clarity of the pricing structure. Leadership has been vocal, on the site and on social media, about how Cost Plus Drugs gets to its final prices in an effort to set a new standard for patient-focused transparency.

For example, every drug is priced with the same markups: a 15% markup supports operations, a $3 charge covers pharmacy labor, and then the usual fixed and variable costs of shipping round out the total. Some savings are minimal; a 60-count of 20mg Fluoxetine, the generic alternative for depression and OCD treatment drug Prozac, costs $4.80 for a Cost Plus Drugs customer, compared to the retail price of $43.80.

Some savings are so stark that they warrant a double take. For a 30-count of 400mg Imatinib, the generic version of leukemia-treatment drug Gleevec, Cost Plus Drugs customers pay $47.50, compared to the retail price of $9,657.40, an enormous difference in cost.

If you are looking for lower pricing on your generic drug purchases, go to https://t.co/LYIIV9Pqzd and sign up ! All drugs are priced at cost plus 15% ! Sign up and share your thoughts and experiences with us ! https://t.co/bFXCMccmvy
— Mark Cuban (@mcuban) January 20, 2022

“We will do whatever it takes to get affordable pharmaceuticals to patients,” said Alex Oshmyansky, CEO of Mark Cuban Cost Plus Drug. “The markup on potentially lifesaving drugs that people depend on is a problem that can’t be ignored. It is imperative that we take action and help expand access to these medications for those who need them most.”

With this cost savings business model, underinsured or uninsured patients who’d be paying close to or full price would see the most immediate benefits. Even insured patients though, according to the company’s site, would pay “less than what you would pay when using your insurance at a typical pharmacy.”

The cost of drugs in the United States has been a problem for some time, garnering attention from President Biden and putting a financial strain on many Americans. According to Kevin Stevenson, Director of Strategic Operations at Providence Healthcare Network in Waco, TX, affecting positive change in this side of the industry is critical, as for patients, it’s truly a life or death situation.

“People who don’t have insurance that are paying out of pocket, oftentimes they skip medications because they take food out of their family’s mouth,” Stevenson said.

The high-profile attention that Cuban’s company, as well as the issue at-large, is getting could be a sign of things to come for healthcare in the United States.

“I think we’re seeing people in healthcare now that are having that more entrepreneurial mindset, that are looking at problems and saying how can we look at it from a different viewpoint to try to solve this,” he said.

Stevenson admitted that change in healthcare can come slowly, but with sharks like Mark Cuban in the water, change could be coming sooner rather than later. 

Your experts belong here

Every story in MarketScale Healthcare starts with a company putting its clinicians, service-line leaders, and field engineers on the record. Buyers are already reading this topic. The only question is whose experts they find.

Service-line buyers vet vendors quietly, and your clinicians become the proof they find while doing it.

Get your team featuredSee how it works15 minutes, straight to a calendar.

Follow Healthcare Insights

Get new expert content in your inbox.

Healthcare: are you visible to AI?

Before they reach out, Healthcare buyers ask AI engines which vendors to trust. Explore how your experts, customers, and partners can become useful content for buyers and AI search.

Free plan

You just read one Healthcare expert. Your company is full of them.

This article was produced through MarketScale. The same platform turns your clinicians, service-line leaders, and field engineers into the articles, video, and social content Healthcare buyers are searching for. Create a free workspace and see it with your own people. No credit card, no demo required.

NPS +73 · 1,000+ creators · 38+ countries

What you get, free

Your own MarketScale workspace, up to 10 people
One professional video edit a month for qualifying companies
Media requests to your crowd, remote recording, AI writing tools
$0, no credit card, nothing that expires

More Healthcare Insights

Most reprocessing audit gaps trace back to training, turnover and leadership

Most reprocessing audit gaps trace back to training, turnover and leadership

Joint Commission findings on its reprocessing standard point mostly to training, turnover, leadership and missing ownership, not sterilizers. CDC epidemiologists and a 2019 review add cleaning verification and manufacturer instructions as the steps to watch. Audit people and process steps as closely as the autoclave.

  • 01Of the Joint Commission's list of reasons hospitals miss reprocessing standard IC.02.02.01, at least eight concern people, priorities and management, so competency records and a named process owner belong in the audit as much as sterilizer logs.
  • 02A structured audit tool that scores compliance step by step, as a 2020 BMC Health Services Research study did across 189 reprocessing cycles, shows where training hours should go; the Nepal hospitals scored best on cleaning and storage and worse on the steps between.

Sep 14, 2026

From Data to Decisions: Leadership, Trust, and AI in Healthcare with Dr. Julia Rehman

Healthcare leaders often struggle to convert abundant data and AI investments into actionable decisions that improve care. Dr. Julia Rehman emphasizes that effective AI integration requires human judgment in the loop, strong governance frameworks, and frontline staff engagement, especially in resource-constrained settings.

  • 01AI should target specific operational challenges like staffing, readmissions, and bed capacity, with humans retaining decision-making authority.
  • 02Few healthcare organizations have governance structures to ensure accountability, audit trails, bias monitoring, and oversight as AI adoption accelerates.
  • 03Data richness without strategic insight and human judgment informed by experience limits the value of technology investments in healthcare.

Sep 14, 2026

Two Radiology Deals Signal Focus on Coverage, Not Scanners

Two Radiology Deals Signal Focus on Coverage, Not Scanners

Colorado Imaging Associates and TRA Medical Imaging announced Sept. 8, 2026 that they are forming Affiliated Radiology to expand physician coverage for a shared health system client, Radiology Business reported. Separately, Align Capital Partners said in late May 2026 it agreed to acquire Boise-based Heritage Imaging, a mobile diagnostic imaging provider operating in 14 states, according to Radiology Business.

  • 01Affiliated Radiology was formed by combining Colorado Imaging Associates and TRA Medical Imaging to expand physician coverage for a shared health system client.
  • 02Heritage Imaging operates mobile diagnostic units across 14 states, providing PET-CT, MRI, nuclear medicine, ultrasound and echocardiography to critical access hospitals and community clinics.
  • 03Health system sourcing teams should request service-level commitments, credentialing procedures, cross-location read routing, and PACS/RIS/EHR integration details before contracting with coverage-focused or mobile imaging arrangements.

Sep 12, 2026

Explore More Healthcare Insights

Read more expert perspectives from across Healthcare.

Browse Healthcare Hub

For B2B teams

Your experts could be publishing here

Stories like this one run on content MarketScale captures from real practitioners. See how your team's expertise becomes coverage in Healthcare and beyond.

Book a 15-minute demo

Or call us. No forms required. We pick up. 214-945-2512