Indika Edirisinghe's research focuses on studying the impact of dietary components on vascular disease, with a particular emphasis on evaluating endothelial function, inflammatory responses, and oxidative stress during acute and chronic interventions. His research methodology involves both in vivo human studies and in vitro human cell culture models. Dr. Edirisinghe has received recognition for his work, including serving as an ad hoc scientific reviewer for the National Center for Complementary and Alternative Medicine at the NIH. He is also a member of the Advisory Board for the MPH Program at Benedictine University in Illinois and holds the position of Vice Chair for the Agricultural and Food Chemistry/Nutritional Chemistry Subdivision at the American Chemical Society.